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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2D
All Species:
21.82
Human Site:
S231
Identified Species:
40
UniProt:
Q14814
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14814
NP_005911.1
521
55938
S231
G
Y
V
S
A
R
A
S
P
G
L
L
P
V
A
Chimpanzee
Pan troglodytes
XP_001165500
521
55889
S231
G
Y
V
S
A
R
A
S
P
G
L
L
P
V
A
Rhesus Macaque
Macaca mulatta
XP_001103222
500
53974
A229
N
G
F
V
N
S
R
A
S
P
N
L
I
G
T
Dog
Lupus familis
XP_547534
525
56508
L231
L
S
P
Q
Q
P
A
L
Q
R
N
S
V
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q63943
514
54974
S231
G
Y
V
S
A
R
A
S
P
G
L
L
P
V
A
Rat
Rattus norvegicus
O89038
507
54350
S231
G
Y
V
S
A
R
A
S
P
G
L
L
P
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507540
505
54598
R231
G
N
G
F
V
N
S
R
A
S
P
N
L
L
G
Chicken
Gallus gallus
Q9W6U8
499
53650
S233
G
V
W
N
S
R
A
S
P
S
L
L
G
T
A
Frog
Xenopus laevis
Q03413
498
54053
S231
G
Y
I
S
A
R
A
S
P
G
L
L
P
V
S
Zebra Danio
Brachydanio rerio
NP_571392
529
57466
P231
Y
V
S
A
R
A
S
P
G
L
L
S
V
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
I231
G
I
A
H
H
L
S
I
K
Q
Q
S
P
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
N13
I
E
I
K
R
I
E
N
A
N
S
R
Q
V
T
Baker's Yeast
Sacchar. cerevisiae
Q12224
676
73465
S231
N
L
N
Q
P
S
S
S
S
S
S
P
S
T
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
53.7
72.5
N.A.
96.1
94.4
N.A.
54.1
54.7
73.6
70.1
N.A.
28
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
63.9
75.8
N.A.
97.1
95.5
N.A.
64.8
64.3
82.5
78.2
N.A.
39.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
100
100
N.A.
6.6
53.3
86.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
6.6
N.A.
100
100
N.A.
20
66.6
100
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.9
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
39
8
54
8
16
0
0
0
0
0
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
62
8
8
0
0
0
0
0
8
39
0
0
8
16
8
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
16
0
0
8
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
0
8
0
8
0
8
54
54
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
16
8
8
8
8
8
0
8
0
8
16
8
0
0
8
% N
% Pro:
0
0
8
0
8
8
0
8
47
8
8
8
47
0
8
% P
% Gln:
0
0
0
16
8
0
0
0
8
8
8
0
8
0
0
% Q
% Arg:
0
0
0
0
16
47
8
8
0
8
0
8
0
0
0
% R
% Ser:
0
8
8
39
8
16
31
54
16
24
16
24
8
16
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
16
% T
% Val:
0
16
31
8
8
0
0
0
0
0
0
0
16
47
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _